HIV and HBV Essay Example | Topics and Well Written Essays - 500 words

HIV and HBV - Essay ExampleThis in vitro study is called transient transfection cell culture systems and has been apply to establish sensitivity or cross resistance to analogues. Imperative in this activity is the acquisition of duodecimal real time data and previous knowledge on the replication and pathogenesis of HIV or HBV. either difference in expression of the transfected cell is identified and analyzed.Another approach is to introduce derivatives from certain sources that clear serve as potent inhibitor of in vitro HIV or HBV replication. For example, synthetic DNA molecules called antisense oligodeoxynucleotides (ODN) were administered to cells transiently and stably transfected with HBV protein encoding plasmids. The cells were observed for any HBV replication and pathogenesis for 48 hours. It was found that there ODN effectively inhibited viral protein expression and replication. ( Karayiannis, 2003)Animal models have also been very useful in understanding the replicatio n and pathogenesis of the computer virus mentioned. Many of the models are nave primates such as chimpanzees, rhesus macaques and Aotus monkeys. HBV or HIV holder animals are administered with potential cures.